CHEMISTRY 252


Spring 1998

Text: 1. W. H. Brown, Organic Chemistry, Saunders College Publishing Co., 1995.

2. B. L. Iverson and S. A. Iverson, Student Study Guide and Problems Book for Organic Chemistry, Volumes 1 and 2, Saunders College Publishing Co., 1995.

Lecturer: (Lecture Section 1; MWF, 9:10 - 10:00 AM)

Professor E. LeGoff Office: 531 Chemistry Building, Phone: 355-9715 (x 146)

Office Hours: Wednesdays 1:30 - 3:30 PM

Lecturer: (Lecture Section 2; MWF, 11:30 - 12:20 PM)

Professor M. Rathke Office: 522 Chemistry Building, Phone: 355-9715 (x 150)

Office Hours: MWF, 10:20 - 11:15 AM

Library: Room 426 Chemistry Bldg. - Course folders and text are on reserve.


Lecture and Reading Schedule
CHAPTERSTOPIC DATES COVERED
Chapters 12, 13, 14Spectroscopy Jan. 14, 16, 19, 23
Chapter 17Aldehydes and Ketones Jan. 26, 28, 30, Feb. 2, 4, 6
Chapter 18Carbohydrates Feb. 9, 11, 13, 18
EXAMCovers: Chapters 12, 13, 14, 17 Feb. 16 (Monday)
Chapter 19Carboxylic Acids Feb. 20, 23, 25, 27, Mar. 2
Chapter 20Carboxylic Acid Derivatives Mar. 4, 6, 16, 18, 20
Chapter 21Enolate Anions Mar. 23, 25, 27
EXAMCovers: Chapters 18, 19, 20 Mar. 30 (Monday)
Chapter 22AminesApr. 1, 3, 6, 8, 10
Chapter 23LipidsApr. 13, 15
Chapter 24Amino Acid and Proteins Apr. 17, 20, 22, 24
EXAMCovers: Chapters 21, 22, 23 Apr. 27 (Monday)
ReviewApril 29, May 1
FINAL EXAMCovers: Chapters 12-24 May 5 (Tuesday) 5:45 PM


Examinations and Grading:

There will be three 50-minute examinations given during the lecture periods (Feb. 16, Mar. 30 and Apr. 27). These will count 200 points each. All exams must be taken in the lecture section in which you are enrolled. The total points you earn and their relationship to your grade in this course will be determined as follows:
Three Exams (200 points each) =600 points
Final Exam= 400 points
Total= 1000 points

Points Earned
Approximate

Percentages


Course Grade
1000 - 850100 - 85% 4.0
849 - 770~84 - 77% 3.5
769 - 700~76 - 70% 3.0
699 - 620~69 - 62% 2.5
619 - 560~61 - 56% 2.0
559 - 470~55 - 47% 1.5
469 - 400~46 - 40% 1.0
399 - 0~39 - 0% 0.0

Missed Exams:

No makeup exams will be given. If you miss an hourly examination your course grade will be calculated by adding the point value (200 pts) of the missed exam to the Final Exam. Thus, if you miss one exam, your Final Exam will count for 600 points; and if you miss two exams, your final will count for 800 points.

Regrading of Exams:

Hourly exams will be returned only during your regularly scheduled recitation meeting following the exam. Any regrading requests must be made at that time to the recitation instructor by means of a signed note in the space provided on the exam. No exam which has left the recitation room in possession of the student will be considered for regrading. The entire exam will be regraded when a request for regrading is made. Unclaimed exams may be obtained from your recitation instructor.

Final Exam:

The final, which is all-inclusive, will be given on Tuesday, May 5, 5:45-7:45 PM. The room locations will be announced during the last week of classes. University rules stipulate that you will receive a 0.0 for the course if you do not take the final exam. The scheduling of a make up for the final exam and the issuing of Incompletes will follow university rules.

Final exams will be kept on file by your instructor for one semester and then destroyed. If you wish to check your final exam, make an appointment with your instructor sometime during the next semester.



Handouts:

At various times, handouts with homework problem assignments, announcements, etc. will be available at the back of the lecture hall as you enter. They will be available only once (except this one). Please take only one copy. If you miss obtaining a handout at lecture, a copy of each handout will be available from the CEM 252 course folder in the Chemistry Department Library (Rm. 426 Chem. Bldg.). Textbooks (Brown), study guides and molecular models are also available in the Chem. Library.

Recitations:

Recitations begin January 19. These periods will be devoted to answering questions, assisting students in problem solving, giving quizzes, and returning and reviewing hourly examinations. Since course records are kept by your recitation instructor, it is critical that you know the recitation instructor's name and your recitation section number by the time of the first exam. For extra help, you may see an instructor during scheduled office hours. Office hours for recitation instructors will be announced separately. Please do not enter graduate labs at other times since dangerous chemicals are always present and potentially dangerous experiments may be in progress.

Policy on Cheating:

Any student caught cheating will receive a grade of 0.0 for the course. In addition, a letter describing the incident will be sent to the chairperson of the chemistry department and to the dean of the student's college.

Study Hints:

We urge you to use the study guides that accompany the Brown textbook. We want to emphasize a few points:

1. Organic chemistry in many ways resembles a new language for you, and you cannot avoid quite a bit of memorizing (vocabulary).

2. To do well, you have to do a lot of writing - write formulas, write equations, so that you can write complex structures quickly. You cannot learn organic chemistry just by reading about it.

3. The best way to do well is to work problems, as many as you possibly can. We will assign some, and the quizzes will be based on them, but try to do as many others as you possibly can. You may consult other chemistry texts in the library for additional problems.

4. While attendance at lectures is not required, experience shows that most people who do not attend regularly do poorly in the course.

5. Organic chemistry is a cumulative subject. If you get behind at the beginning, you will get lost, because every new topic depends on what went before it. So keep up to date; don't get behind.

6. Plan on a minimum of 10 hours/week for study outside of class.

Reviewing CEM 251:

Success in mastering the material in CEM 252 is dependent upon your having a good grasp of the information presented in CEM 251. You should review Chapters 1-11, 15 and 16, paying special attention to structure, nomenclature and reactions. A good method to review this material is to read the Overview Sections of each chapter as presented in Volume 1 of the Study Guide.


Reading and Problem Assignments. Exams will be taken mostly from the assigned problems below. They will be based upon the lecture material and upon the principles and facts exemplified by the assigned problems.
CHAPTERREADING PROBLEMS
12

Mass Spectrometry

12.1 (p. 458), 12.2 (p. 462), 12.3 (p. 466), 12.12, 12.13, 12.15, 12.16, 12.17, 12.18, 12.19, 12.21
13

Nuclear Magnetic Resonance Spectroscopy
13.2 (p. 486), 13.4 (p. 489), 13.5 (p. 494), 13.6 (p. 500), 13.16, 13.17, 13.19, 13.20, 13.21, 13.22, 13.24, 13.25
14
Infrared and Ultraviolet-Visible Spectroscopy 14.2 (p. 525), 14.9 (p. 540), 14.8, 14.10, 14.12 (p. 543), 14.13, 14.19
17

Aldehydes and Ketones

(Omit: Sections 17.8, 17.10, page 679, 17.15B, 17.16C)

17.1 (p. 645), 17.2 (p. 646), 17.4 (p. 658), 17.6 (p. 668), 17.8 (p. 673), 17.10 (p. 678), 17.11 (p. 685), 17.13, 17.14, 17.15, 17.16, 17.22, 17.24, 17.27, 17.36, 17.47, 17.48, 17.51, 17.52, 17.54, 17.58, 17.60, 17.64
18

Carbohydrates

(Omit: pp. 736, 737, 747)

18.1, 18.2, 18.4, 18.6, 18.8, 18.9, 18.10, 18.12, 18.17, 18.18, 18.20,

18.22, 18.24, 18.36, 18.37 a,b,d, 18.38, 18.41, 18.42, 18.43, 18.45b, 18.47

19

Carboxylic Acids

19.1-19.7 a,b,c, 19.8 a,b,h,k, 19.14 a,c,d, 19.15, 19.18, 19.21, 19.25, 19.27
20 & 21



Functional Derivatives of Carboxylic Acids
19.28, 20.1, 20.2, 20.4, 20.7, 20.13, 20.14, 20.20, 20.23, 20.24 a,b,c,e,f, 20.26, 20.27, 20.32, 20.50, 21.2 a, 21.6, 21.8, 21.12, 21.19a, 21.20, 21.21c
22
Amines

(Omit: 22.9 E,F,I; 22.12, 22.13)

22.1-7, 22.9a, 22.12 a,b, 22.19, 22.23, 22.29, 22.36, 22.39, 22.41, 22.46, 22.48, 22.49
23
Lipids 23.1, 23.2, 23.3, 23.9 a,b,c, 23.12
24
Aminoacids and Proteins
24.5, 24.6, 24.8, 24.9, 24.11, 24.19, 24.24, 24.25, 24.30